J.S. Ye, A. Majumdar, B.C. Park, M.H. Black, T.-S. Hsieh, A. Osinski, K.A. Servage, K. Kulkarni, J. Naidoo, N.M. Alto, M.M. Stratton, D. Alfandari, J.M. Ready, K. Pawłowski, D.R. Tomchick, V.S. Tagliabracci (2025) “Bacterial ubiquitin ligase engineered for small molecule and protein target identification” [BioRxiv]
X. Yang, X. Ma, T. Zhao, D.R. Croucher, E.V. Nguyen, K.C. Clark, C. Hu, S.L. Latham, C. Bayly-Jones, V. Nguyen, S. Budnar, S. Shin, L.K. Nguyen, T.R. Cotton, A.C. Chueh, T. Sian, M.M. Stratton, A.M. Ellis-Don, R.J. Daly (2025) “Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple-negative breast cancer” [Nature Comm.]
J.M. Schafer, C.S. Muli, R.A. Heikal, M.A. Dyba, S.G. Tarasov, M.M. Stratton, E.R. Strieter, K.J. Walters (2025) “Optimized isolation of enzymatically active ubiquitin E3 ligase E6AP/UBE3A from mammalian cells” [PubMed]
V. Nguyen, C. Özden, K. Dong, A. Torres-Ocampo, N. Dziedzic, D. Flaherty, J. Huang, S. Sankura, N. Abromson, D. Tomchick, J. Chen, S. Garman, M.M. Stratton, (2025) A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation. [bioRxiv]. Accepted at Nature Comm.
S. Hu, H. Kim, P. Yang, Z. Yu, B. Ludeke, S. Mobilia, J. Pan, M.M. Stratton, Y. Bian, R. Fearns, J. Abraham (2025) “Structural and functional analysis of the Nipah virus polymerase complex” [PubMed]
P.M.F. Rigter, K. Bezstarosti, O.C. Koc#, T.L. Perfitt, J.A.A. Demmers, R.J. Colbran, M.M. Stratton, Y. Elgersma, G.M. van Woerden (2024) “Simultaneous loss of CAMK2A and CAMK2B reveals endogenous in vivo substrates ” [bioRxiv]
X. Yang..., V. Nguyen..., M.M. Stratton..., R. Daly, (2024) Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically ‘actionable’ signaling axis in triple negative breast cancer. [bioRxiv]
D. Narayan..., R. Adafia..., M.M. Stratton..., S. Solbak (2024) Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking and kinase inhibition. [bioRxiv]
P. Rigter..., M. Dunn..., M.M. Stratton..., G. van Woerden (2024) Role of CAMK2D in neurodevelopment and associated conditions. [PubMed]
C. Özden, S. MacManus, R. Adafia, A. Samkutty, A.P. Torres-Ocampo, S.C. Garman, M.M. Stratton, (2024) Ca2+/CaM dependent protein kinase II (CaMKII)α and CaMKIIβ hub domains adopt distinct oligomeric states and stabilities. Protein Science. ; 33(4):e4960. [Wiley]
C. Özden, R. Sloutsky, T. Mitsugi, N. Santos, E. Agnello, C. Gaubitz, J. Foster, E. Lapinskas, E.A. Esposito, T. Saneyoshi, B.A. Kelch, S.C. Garman, Y. Hayashi, M.M. Stratton, (2022) CaMKII binds both substrates and activators at the active site, Cell Reports, 40, 111064. [PubMed]
R. Sloutsky and M. M. Stratton, (2020) Functional Implications of CaMKII Alternative Splicing, The European Journal of Neuroscience, 28, 10.1111/ejn.14761. [PubMed]
A. P. Torres‐Ocampo, C. Özden, A. Hommer, A. Gardella, E. Lapinskas, A. Samkutty, E. Esposito, S. Garman, M. M. Stratton, (2020) Characterization of CaMKIIα holoenzyme stability, Protein Science, 6, 1524-1534. [PubMed]
R. Sloutsky*, N. Dziedzic*, M. J. Dunn, R. M. Bates, A. P. Torres-Ocampo, S. Boopathy, B. Page, J.G. Weeks, L. H. Chao, M. M. Stratton, (2019) Heterogeneity in human hippocampal CaMKII transcripts reveals an allosteric role for the hub domain in activity regulation, Science Signaling, 13, 641, eaaz0240. [PubMed]
G. Ardestani, M. C. West, T. J. Maresca, R. A. Fissore, M. M. Stratton, (2019) FRET-based sensor for CaMKII activity (FRESCA): A useful tool for assessing CaMKII activity in response to Ca2+ oscillations in live cells, J Biol Chem, 31, 11876-11891. [PubMed]
M. S. Eriksen, O. Nikolanienko, E. I. Hallin, S. Grødem, H. J. Bustad, M. I. Flydal, R. O’Connell, T. Hosokawa, D. Lascu, S. Akerkar, J. Cuéllar, J. J. Chambers, G. Muruganandam, R. Loris, T. Kanhema, Y. Hayashi, M. M. Stratton, J. M. Valpuesta, P. Kursula, A. Martinez, C. R. Bramham, (2019) Molecular determinants of Arc oligomerization and formation of virus-like capsids, bioRxiv, 667956. [bioRxiv]
T. Saneyoshi, H. Matsuno, A. Suzuki, H. Murakoshi, N. G. Hedrick, E. Agnello, R. O’Connell, M. M. Stratton, R. Yasuda, Y. Hayashi, (2019) Reciprocal Activation within a Kinase-Effector Complex Underlying Persistence of Structural LTP, Neuron, 102, 6, P1199-1210.E6. [PubMed]
M. Bhattacharyya*, M. M. Stratton*, Catherine Going*, Yongjian Huang, Ethan McSpadden, Anna Elleman, Pawel Burkhwat, Tiago Barros, Evan Williams, John Kuriyan, (2016) Molecular Mechanism of activation-triggered subunit exchange in human CaMKII, eLife, e13405. [PubMed]
M. M. Stratton*, I. H. Lee*, M. Bhattacharyya, S. M. Christensen, L. H. Chao, H. Schulman, J. T. Groves, J. Kuriyan, (2014) Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity, eLife, 3:e01610. [PubMed]
M. M. Stratton, L. H. Chao, H. Schulman, J. Kuriyan, (2013) Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase II, Current opinion in structural biology, 23, 292-301. [PubMed]
L. H. Chao, M. M. Stratton, I. H. Lee, J. Levitz, D. Mandell, T. Kortemme, H. Schulman, J. Kuriyan, (2011) A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme, Cell, 146, 732-745. [PubMed]
M. M. Stratton*, S. McClendon*, D. Eliezer, and S. N. Loh, (2011) Structural characterization of two alternate conformations in a Calbindin D9k-based molecular switch, Biochemistry, 50, 5583-5589. [PubMed]
M. M. Stratton and S. N. Loh, (2011) Converting a protein into a switch for biosensing and functional regulation, Protein Science, 20, 19-29. [PubMed]
M. M. Stratton and S.N. Loh, (2010) On the mechanism of protein fold-switching by a molecular sensor, Proteins, 78, 3260-3269. [PubMed]
M. M. Stratton, T. A. Cutler, J. H. Ha, and S. N. Loh, (2010) Probing local structural fluctuations in myoglobin by size-dependent thiol-disulfide exchange, Protein Science, 19, 1587-1594. [PubMed]
M. M. Stratton, D. M. Mitrea and S. N. Loh, (2008) A Ca2+-sensing molecular switch based on alternate frame protein folding, ACS Chem. Biol., 3, 723-732. [PubMed]
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